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Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization
The pathophysiology of the E150K mutation in the rod opsin gene associated with autosomal recessive retinitis pigmentosa (arRP) has yet to be determined. We generated knock-in mice carrying a single nucleotide change in exon 2 of the rod opsin gene resulting in the E150K mutation. This novel mouse m...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3533307/ https://ncbi.nlm.nih.gov/pubmed/23221340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66176 |
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