Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells

BACKGROUND: Human embryonic stem cells (hESCs) partially recapitulate early embryonic three germ layer development, allowing testing of potential teratogenic hazards. Because use of hESCs is ethically debated, we investigated the potential for human induced pluripotent stem cells (hiPSCs) to replace...

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Detaylı Bibliyografya
Yayımlandı:Stem Cell Res Ther
Asıl Yazarlar: Shinde, Vaibhav, Perumal Srinivasan, Sureshkumar, Henry, Margit, Rotshteyn, Tamara, Hescheler, Jürgen, Rahnenführer, Jörg, Grinberg, Marianna, Meisig, Johannes, Blüthgen, Nils, Waldmann, Tanja, Leist, Marcel, Hengstler, Jan Georg, Sachinidis, Agapios
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2016
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5203708/
https://ncbi.nlm.nih.gov/pubmed/28038682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-016-0449-2
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