Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells

BACKGROUND: Human embryonic stem cells (hESCs) partially recapitulate early embryonic three germ layer development, allowing testing of potential teratogenic hazards. Because use of hESCs is ethically debated, we investigated the potential for human induced pluripotent stem cells (hiPSCs) to replace...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Stem Cell Res Ther
Prif Awduron: Shinde, Vaibhav, Perumal Srinivasan, Sureshkumar, Henry, Margit, Rotshteyn, Tamara, Hescheler, Jürgen, Rahnenführer, Jörg, Grinberg, Marianna, Meisig, Johannes, Blüthgen, Nils, Waldmann, Tanja, Leist, Marcel, Hengstler, Jan Georg, Sachinidis, Agapios
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2016
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5203708/
https://ncbi.nlm.nih.gov/pubmed/28038682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-016-0449-2
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