Kinetic modeling of stem cell transcriptome dynamics to identify regulatory modules of normal and disturbed neuroectodermal differentiation

Thousands of transcriptome data sets are available, but approaches for their use in dynamic cell response modelling are few, especially for processes affected simultaneously by two orthogonal influencing variables. We approached this problem for neuroepithelial development of human pluripotent stem...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Meisig, Johannes, Dreser, Nadine, Kapitza, Marion, Henry, Margit, Rotshteyn, Tamara, Rahnenführer, Jörg, Hengstler, Jan G, Sachinidis, Agapios, Waldmann, Tanja, Leist, Marcel, Blüthgen, Nils
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Computational Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736781/
https://ncbi.nlm.nih.gov/pubmed/33245762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1089
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