Kinetic modeling of stem cell transcriptome dynamics to identify regulatory modules of normal and disturbed neuroectodermal differentiation

Thousands of transcriptome data sets are available, but approaches for their use in dynamic cell response modelling are few, especially for processes affected simultaneously by two orthogonal influencing variables. We approached this problem for neuroepithelial development of human pluripotent stem...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Meisig, Johannes, Dreser, Nadine, Kapitza, Marion, Henry, Margit, Rotshteyn, Tamara, Rahnenführer, Jörg, Hengstler, Jan G, Sachinidis, Agapios, Waldmann, Tanja, Leist, Marcel, Blüthgen, Nils
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
Materias:
Computational Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736781/
https://ncbi.nlm.nih.gov/pubmed/33245762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1089
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