From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects

The superordinate principles governing the transcriptome response of differentiating cells exposed to drugs are still unclear. Often, it is assumed that toxicogenomics data reflect the immediate mode of action (MoA) of drugs. Alternatively, transcriptome changes could describe altered differentiatio...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Balmer, Nina V., Klima, Stefanie, Rempel, Eugen, Ivanova, Violeta N., Kolde, Raivo, Weng, Matthias K., Meganathan, Kesavan, Henry, Margit, Sachinidis, Agapios, Berthold, Michael R., Hengstler, Jan G., Rahnenführer, Jörg, Waldmann, Tanja, Leist, Marcel
פורמט: Artigo
שפה:Inglês
יצא לאור: Springer Berlin Heidelberg 2014
נושאים:
Reproductive Toxicology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067541/
https://ncbi.nlm.nih.gov/pubmed/24935251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-014-1279-6
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