Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation

Efficient protocols to differentiate human pluripotent stem cells to various tissues in combination with -omics technologies opened up new horizons for in vitro toxicity testing of potential drugs. To provide a solid scientific basis for such assays, it will be important to gain quantitative informa...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Shinde, Vaibhav, Klima, Stefanie, Sureshkumar, Perumal Srinivasan, Meganathan, Kesavan, Jagtap, Smita, Rempel, Eugen, Rahnenführer, Jörg, Hengstler, Jan Georg, Waldmann, Tanja, Hescheler, Jürgen, Leist, Marcel, Sachinidis, Agapios
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2015
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544843/
https://ncbi.nlm.nih.gov/pubmed/26132533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52333
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