Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation

Efficient protocols to differentiate human pluripotent stem cells to various tissues in combination with -omics technologies opened up new horizons for in vitro toxicity testing of potential drugs. To provide a solid scientific basis for such assays, it will be important to gain quantitative informa...

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Veröffentlicht in:J Vis Exp
Hauptverfasser: Shinde, Vaibhav, Klima, Stefanie, Sureshkumar, Perumal Srinivasan, Meganathan, Kesavan, Jagtap, Smita, Rempel, Eugen, Rahnenführer, Jörg, Hengstler, Jan Georg, Waldmann, Tanja, Hescheler, Jürgen, Leist, Marcel, Sachinidis, Agapios
Format: Artigo
Sprache:Inglês
Veröffentlicht: MyJove Corporation 2015
Schlagworte:
Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544843/
https://ncbi.nlm.nih.gov/pubmed/26132533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52333
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