Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Tox(ukn) and STOP-Tox(ukk) tests

Stem cell-based in vitro test systems can recapitulate specific phases of human development. In the UKK test system, human pluripotent stem cells (hPSCs) randomly differentiate into cells of the three germ layers and their derivatives. In the UKN1 test system, hPSCs differentiate into early neural p...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Arch Toxicol
المؤلفون الرئيسيون: Shinde, Vaibhav, Hoelting, Lisa, Srinivasan, Sureshkumar Perumal, Meisig, Johannes, Meganathan, Kesavan, Jagtap, Smita, Grinberg, Marianna, Liebing, Julia, Bluethgen, Nils, Rahnenführer, Jörg, Rempel, Eugen, Stoeber, Regina, Schildknecht, Stefan, Förster, Sunniva, Godoy, Patricio, van Thriel, Christoph, Gaspar, John Antonydas, Hescheler, Jürgen, Waldmann, Tanja, Hengstler, Jan G., Leist, Marcel, Sachinidis, Agapios
التنسيق: Artigo
اللغة:Inglês
منشور في: Springer Berlin Heidelberg 2016
الموضوعات:
In vitro Systems
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5306084/
https://ncbi.nlm.nih.gov/pubmed/27188386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1741-8
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