MicroRNAs as early toxicity signatures of doxorubicin in human-induced pluripotent stem cell-derived cardiomyocytes

An in depth investigation at the genomic level is needed to identify early human-relevant cardiotoxicity biomarkers that are induced by drugs and environmental toxicants. The main objective of this study was to investigate the role of microRNAs (miRNAs) as cardiotoxicity biomarkers using human-induc...

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Vydáno v:Arch Toxicol
Hlavní autoři: Chaudhari, Umesh, Nemade, Harshal, Gaspar, John Antonydas, Hescheler, Jürgen, Hengstler, Jan G., Sachinidis, Agapios
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2016
Témata:
Organ Toxicity and Mechanisms
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104806/
https://ncbi.nlm.nih.gov/pubmed/26842497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1668-0
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