Arginase Is Essential for Survival of Leishmania donovani Promastigotes but Not Intracellular Amastigotes

Studies of Leishmania donovani have shown that both ornithine decarboxylase and spermidine synthase, two enzymes of the polyamine biosynthetic pathway, are critical for promastigote proliferation and required for maximum infection in mice. However, the importance of arginase (ARG), the first enzyme...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Boitz, Jan M., Gilroy, Caslin A., Olenyik, Tamara D., Paradis, Dustin, Perdeh, Jasmine, Dearman, Kristie, Davis, Madison J., Yates, Phillip A., Li, Yuexin, Riscoe, Michael K., Ullman, Buddy, Roberts, Sigrid C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5203656/
https://ncbi.nlm.nih.gov/pubmed/27795357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00554-16
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