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Spermidine Synthase Is Required for Virulence of Leishmania donovani

Genetic lesions in the polyamine biosynthetic pathway of Leishmania donovani, the causal agent of visceral leishmaniasis, are conditionally lethal mutations that render the insect vector form of the parasite auxotrophic for polyamines. Recently, we have demonstrated that a Δodc L. donovani null muta...

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Bibliografski detalji
Glavni autori: Gilroy, Caslin, Olenyik, Tamara, Roberts, Sigrid C., Ullman, Buddy
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191959/
https://ncbi.nlm.nih.gov/pubmed/21536795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00073-11
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