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Spermidine Synthase Is Required for Virulence of Leishmania donovani

Genetic lesions in the polyamine biosynthetic pathway of Leishmania donovani, the causal agent of visceral leishmaniasis, are conditionally lethal mutations that render the insect vector form of the parasite auxotrophic for polyamines. Recently, we have demonstrated that a Δodc L. donovani null muta...

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Bibliografiset tiedot
Päätekijät: Gilroy, Caslin, Olenyik, Tamara, Roberts, Sigrid C., Ullman, Buddy
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2011
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191959/
https://ncbi.nlm.nih.gov/pubmed/21536795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00073-11
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