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Spermidine Synthase Is Required for Virulence of Leishmania donovani

Genetic lesions in the polyamine biosynthetic pathway of Leishmania donovani, the causal agent of visceral leishmaniasis, are conditionally lethal mutations that render the insect vector form of the parasite auxotrophic for polyamines. Recently, we have demonstrated that a Δodc L. donovani null muta...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gilroy, Caslin, Olenyik, Tamara, Roberts, Sigrid C., Ullman, Buddy
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191959/
https://ncbi.nlm.nih.gov/pubmed/21536795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00073-11
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