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Oral putrescine restores virulence of ornithine decarboxylase-deficient Leishmania donovani in mice

Administration of putrescine as a 1% solution in the drinking water ameliorated the profound loss of virulence exhibited by ornithine decarboxylase (ODC) deficient Leishmania donovani in mice. Furthermore, supplying α-difluoromethylornithine, an ODC inhibitor, at 2% in the drinking water reduced but...

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Bibliografiska uppgifter
Huvudupphovsmän: Olenyik, Tamara, Gilroy, Caslin, Ullman, Buddy
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042038/
https://ncbi.nlm.nih.gov/pubmed/21182873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2010.12.004
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