Direct Repression of FLIP Expression by c-myc Is a Major Determinant of TRAIL Sensitivity

Tumor necrosis factor alpha (TNF-α)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF-α family of death receptor ligands and holds great therapeutic potential as a tumor cell-specific cytotoxic agent. Using a panel of established tumor cell lines and normal cells, we found a significa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ricci, M. Stacey, Jin, Zhaoyu, Dews, Michael, Yu, Duonan, Thomas-Tikhonenko, Andrei, Dicker, David T., El-Deiry, Wafik S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC516765/
https://ncbi.nlm.nih.gov/pubmed/15367674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.19.8541-8555.2004
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