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Regulation of the human TRAIL gene

TRAIL is a member of the TNF superfamily that induces tumor-selective cell death by engaging the pro-apoptotic death receptors DR4 and DR5. The antitumor potential of the TRAIL pathway has been targeted by several therapeutic approaches including recombinant TRAIL and TRAIL-receptor agonist antibodi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Allen, Joshua E., El-Deiry, Wafik S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469471/
https://ncbi.nlm.nih.gov/pubmed/22892844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.21354
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