NK cells converge lytic granules to promote cytotoxicity and prevent bystander killing

Natural killer (NK) cell activation triggers sequential cellular events leading to destruction of diseased cells. We previously identified lytic granule convergence, a dynein- and integrin signal–dependent movement of lysosome-related organelles to the microtubule-organizing center, as an early step...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Cell Biol
Hlavní autoři: Hsu, Hsiang-Ting, Mace, Emily M., Carisey, Alexandre F., Viswanath, Dixita I., Christakou, Athanasia E., Wiklund, Martin, Önfelt, Björn, Orange, Jordan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5166499/
https://ncbi.nlm.nih.gov/pubmed/27903610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201604136
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky