NK cells converge lytic granules to promote cytotoxicity and prevent bystander killing

Natural killer (NK) cell activation triggers sequential cellular events leading to destruction of diseased cells. We previously identified lytic granule convergence, a dynein- and integrin signal–dependent movement of lysosome-related organelles to the microtubule-organizing center, as an early step...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Cell Biol
Päätekijät: Hsu, Hsiang-Ting, Mace, Emily M., Carisey, Alexandre F., Viswanath, Dixita I., Christakou, Athanasia E., Wiklund, Martin, Önfelt, Björn, Orange, Jordan S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2016
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5166499/
https://ncbi.nlm.nih.gov/pubmed/27903610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201604136
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