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NK cells converge lytic granules to promote cytotoxicity and prevent bystander killing
Natural killer (NK) cell activation triggers sequential cellular events leading to destruction of diseased cells. We previously identified lytic granule convergence, a dynein- and integrin signal–dependent movement of lysosome-related organelles to the microtubule-organizing center, as an early step...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5166499/ https://ncbi.nlm.nih.gov/pubmed/27903610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201604136 |
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