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WIP is essential for lytic granule polarization and NK cell cytotoxicity
Natural killer (NK) cells play important roles in host immunity by killing virus-infected and tumor cells. Killing of the target cell is achieved by formation of an immune synapse and localized secretion of lytic granules containing perforin and granzymes. Here, we demonstrate that Wiskott–Aldrich s...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268177/ https://ncbi.nlm.nih.gov/pubmed/18258743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711593105 |
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