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Many NK cell receptors activate ERK2 and JNK1 to trigger microtubule organizing center and granule polarization and cytotoxicity

Natural killer (NK) cells are components of the innate immune system that recognize and kill tumor or virus-infected target cells through specific NK activating receptor/ligand interactions. Lymphocyte function-associated antigen (LFA)-1 and its ligand ICAM-1 are also required to initiate conjugatio...

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Detalles Bibliográficos
Main Authors: Chen, Xi, Trivedi, Prachi P., Ge, Baoxue, Krzewski, Konrad, Strominger, Jack L.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851054/
https://ncbi.nlm.nih.gov/pubmed/17395718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611655104
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