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Formation of a WIP-, WASp-, actin-, and myosin IIA–containing multiprotein complex in activated NK cells and its alteration by KIR inhibitory signaling

The tumor natural killer (NK) cell line YTS was used to examine the cytoskeletal rearrangements required for cytolysis. A multiprotein complex weighing ∼1.3 mD and consisting of WASp-interacting protein (WIP), Wiskott-Aldrich syndrome protein (WASp), actin, and myosin IIA that formed during NK cell...

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Bibliografiske detaljer
Main Authors: Krzewski, Konrad, Chen, Xi, Orange, Jordan S., Strominger, Jack L.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063796/
https://ncbi.nlm.nih.gov/pubmed/16606694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200509076
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