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Distinct Integrin-Dependent Signals Define Requirements for Lytic Granule Convergence and Polarization in Natural Killer Cells

Lytic granules in natural killer (NK) cells represent a dangerous cargo that is targeted for secretion to destroy diseased cells. The appropriate management of these organelles enables the mounting of a precise and valuable host defense. The process of NK cell adhesion to a target cell through engag...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Hsu, Hsiang-Ting, Orange, Jordan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369380/
https://ncbi.nlm.nih.gov/pubmed/25292212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005816
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