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Rapid activation receptor– or IL-2–induced lytic granule convergence in human natural killer cells requires Src, but not downstream signaling

Natural killer (NK) cells participate in host defense by surveying for and ultimately killing virally infected or malignant target cells. NK cell cytotoxicity is a tightly regulated process that proceeds stepwise from adhesion and activation to the secretion of preformed lytic granule contents onto...

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Detaylı Bibliyografya
Asıl Yazarlar: James, Ashley Mentlik, Hsu, Hsiang-Ting, Dongre, Prachi, Uzel, Gulbu, Mace, Emily M., Banerjee, Pinaki P., Orange, Jordan S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617630/
https://ncbi.nlm.nih.gov/pubmed/23380740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-437012
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