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Rapid Lytic Granule Convergence to the MTOC in Natural Killer Cells Is Dependent on Dynein But Not Cytolytic Commitment

Natural killer cells are lymphocytes specialized to participate in host defense through their innate ability to mediate cytotoxicity by secreting the contents of preformed secretory lysosomes (lytic granules) directly onto a target cell. This form of directed secretion requires the formation of an i...

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Bibliografische gegevens
Hoofdauteurs: Mentlik, Ashley N., Sanborn, Keri B., Holzbaur, Erika L., Orange, Jordan S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893988/
https://ncbi.nlm.nih.gov/pubmed/20444980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-11-0930
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