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Rapid Lytic Granule Convergence to the MTOC in Natural Killer Cells Is Dependent on Dynein But Not Cytolytic Commitment

Natural killer cells are lymphocytes specialized to participate in host defense through their innate ability to mediate cytotoxicity by secreting the contents of preformed secretory lysosomes (lytic granules) directly onto a target cell. This form of directed secretion requires the formation of an i...

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書誌詳細
主要な著者: Mentlik, Ashley N., Sanborn, Keri B., Holzbaur, Erika L., Orange, Jordan S.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893988/
https://ncbi.nlm.nih.gov/pubmed/20444980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-11-0930
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