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Measurement of lytic granule convergence after formation of an NK cell immunological synapse

Natural killer (NK) cells contain specialized lysosome-related organelles termed lytic granules allowing them to mediate cytotoxicity against tumorigenic or virally infected target cells. NK cells polarize their lytic granules towards a target cell via the microtubule-organizing center (MTOC). Prior...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Hsu, Hsiang-Ting, Carisey, Alexandre F., Orange, Jordan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861262/
https://ncbi.nlm.nih.gov/pubmed/28255722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6881-7_31
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