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NK Cell Lytic Granules are Highly Motile at the Immunological Synapse and Require F-Actin for Post-degranulation Persistence()
The formation of a dynamic, actin-rich immunological synapse (IS)() and the polarization of cytolytic granules towards target cells are essential to the cytotoxic function of NK cells. Following polarization, lytic granules navigate through the pervasive actin network at the IS in order to degranula...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3558996/ https://ncbi.nlm.nih.gov/pubmed/23066148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201296 |
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