Učitavanje...
Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase
The active RNA-dependent RNA polymerase of poliovirus, 3D(pol), is generated by cleavage of the 3CD(pro) precursor protein, a protease that has no polymerase activity despite containing the entire polymerase domain. By intentionally disrupting a known and persistent crystal packing interaction, we h...
Spremljeno u:
| Izdano u: | EMBO J |
|---|---|
| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2004
|
| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC516629/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15306852/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600357 |
| Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|