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High-throughput Screening Identification of Poliovirus RNA-dependent RNA Polymerase Inhibitors
Viral RNA-dependent RNA polymerase (RdRP) enzymes are essential for the replication of positive-strand RNA viruses and established targets for the development of selective antiviral therapeutics. In this work we have carried out a high-throughput screen of 154,267 compounds to identify poliovirus po...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159743/ https://ncbi.nlm.nih.gov/pubmed/21722674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2011.06.006 |
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