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Poliovirus Polymerase Leu420 Facilitates RNA Recombination and Ribavirin Resistance

RNA recombination is important in the formation of picornavirus species groups and the ongoing evolution of viruses within species groups. In this study, we examined the structure and function of poliovirus polymerase, 3D(pol), as it relates to RNA recombination. Recombination occurs when nascent RN...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Kempf, Brian J., Peersen, Olve B., Barton, David J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021434/
https://ncbi.nlm.nih.gov/pubmed/27412593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00078-16
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