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Poliovirus Polymerase Leu420 Facilitates RNA Recombination and Ribavirin Resistance
RNA recombination is important in the formation of picornavirus species groups and the ongoing evolution of viruses within species groups. In this study, we examined the structure and function of poliovirus polymerase, 3D(pol), as it relates to RNA recombination. Recombination occurs when nascent RN...
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| Veröffentlicht in: | J Virol |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5021434/ https://ncbi.nlm.nih.gov/pubmed/27412593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00078-16 |
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