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Poliovirus Polymerase Leu420 Facilitates RNA Recombination and Ribavirin Resistance

RNA recombination is important in the formation of picornavirus species groups and the ongoing evolution of viruses within species groups. In this study, we examined the structure and function of poliovirus polymerase, 3D(pol), as it relates to RNA recombination. Recombination occurs when nascent RN...

詳細記述

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書誌詳細
出版年:J Virol
主要な著者: Kempf, Brian J., Peersen, Olve B., Barton, David J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021434/
https://ncbi.nlm.nih.gov/pubmed/27412593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00078-16
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