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Poliovirus Polymerase Leu420 Facilitates RNA Recombination and Ribavirin Resistance

RNA recombination is important in the formation of picornavirus species groups and the ongoing evolution of viruses within species groups. In this study, we examined the structure and function of poliovirus polymerase, 3D(pol), as it relates to RNA recombination. Recombination occurs when nascent RN...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Kempf, Brian J., Peersen, Olve B., Barton, David J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021434/
https://ncbi.nlm.nih.gov/pubmed/27412593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00078-16
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