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Polyprotein Context Regulates the Activity of Poliovirus 2C(ATPase) Bound to Bilayer Nanodiscs

Positive-strand RNA viruses generally replicate in large membrane-associated complexes. For poliovirus, these replication complexes are anchored to the membrane via the viral 2B, 2C, and 3A proteins. 2C is an AAA+ family ATPase that plays a key role in host cell membrane rearrangement, is a putative...

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Bibliografski detalji
Glavni autori: Springer, Courtney L., Huntoon, Harrison P., Peersen, Olve B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648184/
https://ncbi.nlm.nih.gov/pubmed/23514879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03491-12
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