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Structural Features of a Picornavirus Polymerase Involved in the Polyadenylation of Viral RNA

Picornaviruses have 3′ polyadenylated RNA genomes, but the mechanisms by which these genomes are polyadenylated during viral replication remain obscure. Based on prior studies, we proposed a model wherein the poliovirus RNA-dependent RNA polymerase (3D(pol)) uses a reiterative transcription mechanis...

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Detalhes bibliográficos
Main Authors: Kempf, Brian J., Kelly, Michelle M., Springer, Courtney L., Peersen, Olve B., Barton, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648189/
https://ncbi.nlm.nih.gov/pubmed/23468507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02590-12
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