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Structural Features of a Picornavirus Polymerase Involved in the Polyadenylation of Viral RNA

Picornaviruses have 3′ polyadenylated RNA genomes, but the mechanisms by which these genomes are polyadenylated during viral replication remain obscure. Based on prior studies, we proposed a model wherein the poliovirus RNA-dependent RNA polymerase (3D(pol)) uses a reiterative transcription mechanis...

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Bibliografski detalji
Glavni autori: Kempf, Brian J., Kelly, Michelle M., Springer, Courtney L., Peersen, Olve B., Barton, David J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648189/
https://ncbi.nlm.nih.gov/pubmed/23468507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02590-12
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