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Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions
The viral RNA-dependent RNA polymerases show a conserved structure where the fingers domain interacts with the top of the thumb domain to create a tunnel through which nucleotide triphosphates reach the active site. We have solved the crystal structures of poliovirus polymerase (3D(pol)) in complex...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1941708/ https://ncbi.nlm.nih.gov/pubmed/17223130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.11.070 |
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