PKC-θ knockout mice are protected from fat-induced insulin resistance

Insulin resistance plays a primary role in the development of type 2 diabetes and may be related to alterations in fat metabolism. Recent studies have suggested that local accumulation of fat metabolites inside skeletal muscle may activate a serine kinase cascade involving protein kinase C–θ (PKC-θ)...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Kim, Jason K., Fillmore, Jonathan J., Sunshine, Mary Jean, Albrecht, Bjoern, Higashimori, Takamasa, Kim, Dong-Wook, Liu, Zhen-Xiang, Soos, Timothy J., Cline, Gary W., O’Brien, William R., Littman, Dan R., Shulman, Gerald I.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2004
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC516267/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15372106/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI22230
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky