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Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans

Muscle insulin resistance is a key feature of obesity and type 2 diabetes and is strongly associated with increased intramyocellular lipid content and inflammation. However, the cellular and molecular mechanisms responsible for causing muscle insulin resistance in humans are still unclear. To addres...

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Bibliografski detalji
Glavni autori: Szendroedi, Julia, Yoshimura, Toru, Phielix, Esther, Koliaki, Chrysi, Marcucci, Mellissa, Zhang, Dongyan, Jelenik, Tomas, Müller, Janette, Herder, Christian, Nowotny, Peter, Shulman, Gerald I., Roden, Michael
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084449/
https://ncbi.nlm.nih.gov/pubmed/24979806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409229111
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