Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans

Muscle insulin resistance is a key feature of obesity and type 2 diabetes and is strongly associated with increased intramyocellular lipid content and inflammation. However, the cellular and molecular mechanisms responsible for causing muscle insulin resistance in humans are still unclear. To addres...

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Detalhes bibliográficos
Principais autores: Szendroedi, Julia, Yoshimura, Toru, Phielix, Esther, Koliaki, Chrysi, Marcucci, Mellissa, Zhang, Dongyan, Jelenik, Tomas, Müller, Janette, Herder, Christian, Nowotny, Peter, Shulman, Gerald I., Roden, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084449/
https://ncbi.nlm.nih.gov/pubmed/24979806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409229111
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