Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program

In general, cell fate is determined primarily by transcription factors, followed by epigenetic mechanisms fixing the status. While the importance of transcription factors controlling cell fate has been well characterized, epigenetic regulation of cell fate maintenance remains to be elucidated. Here...

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Veröffentlicht in:Genes Dev
Hauptverfasser: Ikawa, Tomokatsu, Masuda, Kyoko, Endo, Takaho A., Endo, Mitsuhiro, Isono, Kyoichi, Koseki, Yoko, Nakagawa, Rinako, Kometani, Kohei, Takano, Junichiro, Agata, Yasutoshi, Katsura, Yoshimoto, Kurosaki, Tomohiro, Vidal, Miguel, Koseki, Haruhiko, Kawamoto, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159663/
https://ncbi.nlm.nih.gov/pubmed/27913604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.290593.116
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