Mammalian Polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1

Polycomb group (PcG) proteins are responsible for the stable repression of homeotic (Hox) genes by forming multimeric protein complexes. We show (1) physical interaction between components of the U2 small nuclear ribonucleoprotein particle (U2 snRNP), including Sf3b1 and PcG proteins Zfp144 and Rnf2...

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Bibliografische gegevens
Gepubliceerd in:Genes Dev
Hoofdauteurs: Isono, Kyoichi, Mizutani-Koseki, Yoko, Komori, Toshihisa, Schmidt-Zachmann, Marion S., Koseki, Haruhiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2005
Onderwerpen:
Research Communications
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC551574/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15741318/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1284605
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