Mammalian Polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1

Polycomb group (PcG) proteins are responsible for the stable repression of homeotic (Hox) genes by forming multimeric protein complexes. We show (1) physical interaction between components of the U2 small nuclear ribonucleoprotein particle (U2 snRNP), including Sf3b1 and PcG proteins Zfp144 and Rnf2...

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Hauptverfasser: Isono, Kyoichi, Mizutani-Koseki, Yoko, Komori, Toshihisa, Schmidt-Zachmann, Marion S., Koseki, Haruhiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2005
Schlagworte:
Research Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC551574/
https://ncbi.nlm.nih.gov/pubmed/15741318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1284605
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