Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program

In general, cell fate is determined primarily by transcription factors, followed by epigenetic mechanisms fixing the status. While the importance of transcription factors controlling cell fate has been well characterized, epigenetic regulation of cell fate maintenance remains to be elucidated. Here...

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Vydáno v:Genes Dev
Hlavní autoři: Ikawa, Tomokatsu, Masuda, Kyoko, Endo, Takaho A., Endo, Mitsuhiro, Isono, Kyoichi, Koseki, Yoko, Nakagawa, Rinako, Kometani, Kohei, Takano, Junichiro, Agata, Yasutoshi, Katsura, Yoshimoto, Kurosaki, Tomohiro, Vidal, Miguel, Koseki, Haruhiko, Kawamoto, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159663/
https://ncbi.nlm.nih.gov/pubmed/27913604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.290593.116
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