Three-step transcriptional priming that drives the commitment of multipotent progenitors toward B cells

Stem cell fate is orchestrated by core transcription factors (TFs) and epigenetic modifications. Although regulatory genes that control cell type specification are identified, the transcriptional circuit and the cross-talk among regulatory factors during cell fate decisions remain poorly understood....

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Detalles Bibliográficos
Publicado en:Genes Dev
Autores principales: Miyai, Tomohiro, Takano, Junichiro, Endo, Takaho A., Kawakami, Eiryo, Agata, Yasutoshi, Motomura, Yasutaka, Kubo, Masato, Kashima, Yukie, Suzuki, Yutaka, Kawamoto, Hiroshi, Ikawa, Tomokatsu
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830925/
https://ncbi.nlm.nih.gov/pubmed/29440259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.309575.117
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