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E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment
The helix-loop-helix protein, E47, is essential for both B- and T-lineage development. Here we demonstrate that in vitro E47 and Notch signaling act in concert to promote T cell development from fetal hematopoieitic progenitors and to restrain development into the natural killer and myeloid cell lin...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2121213/ https://ncbi.nlm.nih.gov/pubmed/16682500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060268 |
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