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Hierarchy of Notch–Delta interactions promoting T cell lineage commitment and maturation

Notch1 (N1) receptor signaling is essential and sufficient for T cell development, and recently developed in vitro culture systems point to members of the Delta family as being the physiological N1 ligands. We explored the ability of Delta1 (DL1) and DL4 to induce T cell lineage commitment and/or ma...

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Bibliografische gegevens
Hoofdauteurs: Besseyrias, Valerie, Fiorini, Emma, Strobl, Lothar J., Zimber-Strobl, Ursula, Dumortier, Alexis, Koch, Ute, Arcangeli, Marie-Laure, Ezine, Sophie, MacDonald, H. Robson, Radtke, Freddy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118717/
https://ncbi.nlm.nih.gov/pubmed/17261636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061442
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