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Hierarchy of Notch–Delta interactions promoting T cell lineage commitment and maturation
Notch1 (N1) receptor signaling is essential and sufficient for T cell development, and recently developed in vitro culture systems point to members of the Delta family as being the physiological N1 ligands. We explored the ability of Delta1 (DL1) and DL4 to induce T cell lineage commitment and/or ma...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118717/ https://ncbi.nlm.nih.gov/pubmed/17261636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061442 |
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