Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma

Pancreatic cancer is one of the most fatal malignancies lacking effective therapies. Notch signaling is a key regulator of cell fate specification and pancreatic cancer development; however, the role of individual Notch receptors and downstream signaling is largely unknown. Here, we show that Notch2...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Mazur, Pawel K., Einwächter, Henrik, Lee, Marcel, Sipos, Bence, Nakhai, Hassan, Rad, Roland, Zimber-Strobl, Ursula, Strobl, Lothar J., Radtke, Freddy, Klöppel, Günter, Schmid, Roland M., Siveke, Jens T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922150/
https://ncbi.nlm.nih.gov/pubmed/20624967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002423107
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados