Aberrant Methylation of Preproenkephalin and p16 Genes in Pancreatic Intraepithelial Neoplasia and Pancreatic Ductal Adenocarcinoma

Pancreatic intraductal neoplasia (PanIN) is thought to be the precursor to infiltrating pancreatic ductal adenocarcinoma. We have previously shown that the preproenkephalin (ppENK) and p16 genes are aberrantly methylated in pancreatic adenocarcinoma. In this study we define the methylation status of...

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Detalhes bibliográficos
Main Authors: Fukushima, Noriyoshi, Sato, Norihiro, Ueki, Takashi, Rosty, Christophe, Walter, Kimberly M., Wilentz, Robb E., Yeo, Charles J., Hruban, Ralph H., Goggins, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850889/
https://ncbi.nlm.nih.gov/pubmed/12000709
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