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Aberrant Methylation of Preproenkephalin and p16 Genes in Pancreatic Intraepithelial Neoplasia and Pancreatic Ductal Adenocarcinoma

Pancreatic intraductal neoplasia (PanIN) is thought to be the precursor to infiltrating pancreatic ductal adenocarcinoma. We have previously shown that the preproenkephalin (ppENK) and p16 genes are aberrantly methylated in pancreatic adenocarcinoma. In this study we define the methylation status of...

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Bibliografiske detaljer
Main Authors: Fukushima, Noriyoshi, Sato, Norihiro, Ueki, Takashi, Rosty, Christophe, Walter, Kimberly M., Wilentz, Robb E., Yeo, Charles J., Hruban, Ralph H., Goggins, Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850889/
https://ncbi.nlm.nih.gov/pubmed/12000709
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