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Aberrant Methylation of Preproenkephalin and p16 Genes in Pancreatic Intraepithelial Neoplasia and Pancreatic Ductal Adenocarcinoma

Pancreatic intraductal neoplasia (PanIN) is thought to be the precursor to infiltrating pancreatic ductal adenocarcinoma. We have previously shown that the preproenkephalin (ppENK) and p16 genes are aberrantly methylated in pancreatic adenocarcinoma. In this study we define the methylation status of...

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Autors principals: Fukushima, Noriyoshi, Sato, Norihiro, Ueki, Takashi, Rosty, Christophe, Walter, Kimberly M., Wilentz, Robb E., Yeo, Charles J., Hruban, Ralph H., Goggins, Michael
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850889/
https://ncbi.nlm.nih.gov/pubmed/12000709
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