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Canonical notch signaling functions as a commitment switch in the epidermal lineage

Mammalian epidermis consists of a basal layer of proliferative progenitors that gives rise to multiple differentiating layers to provide a waterproof envelope covering the skin surface. To accomplish this, progenitor cells must detach from the basal layer, move upward, and execute a terminal differe...

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Detalhes bibliográficos
Main Authors: Blanpain, Cédric, Lowry, William E., Pasolli, H. Amalia, Fuchs, Elaine
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1620020/
https://ncbi.nlm.nih.gov/pubmed/17079689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1477606
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