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Asymmetric Cell Divisions Promote Notch-Dependent Epidermal Differentiation

Stem and progenitor cells utilize asymmetric cell divisions to balance proliferation and differentiation. Evidence from lower eukaryotes shows that this process is regulated by proteins asymmetrically distributed at the cell cortex during mitosis: (1) Par3-Par6-aPKC, conferring polarity; (2) Gαi-LGN...

詳細記述

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書誌詳細
主要な著者: Williams, Scott E., Beronja, Slobodan, Pasolli, H. Amalia, Fuchs, Elaine
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077085/
https://ncbi.nlm.nih.gov/pubmed/21331036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09793
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