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Asymmetric Cell Divisions Promote Notch-Dependent Epidermal Differentiation
Stem and progenitor cells utilize asymmetric cell divisions to balance proliferation and differentiation. Evidence from lower eukaryotes shows that this process is regulated by proteins asymmetrically distributed at the cell cortex during mitosis: (1) Par3-Par6-aPKC, conferring polarity; (2) Gαi-LGN...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077085/ https://ncbi.nlm.nih.gov/pubmed/21331036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09793 |
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