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Asymmetric cell divisions promote stratification and differentiation of mammalian skin

The epidermis is a stratified squamous epithelium forming the barrier that excludes harmful microbes and retains body fluids. To perform these functions, proliferative basal cells in the innermost layer periodically detach from an underlying basement membrane of extracellular matrix, move outward an...

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Détails bibliographiques
Auteurs principaux: Lechler, Terry, Fuchs, Elaine
Format: Artigo
Langue:Inglês
Publié: 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1399371/
https://ncbi.nlm.nih.gov/pubmed/16094321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03922
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