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Asymmetric partitioning of transfected DNA during mammalian cell division

Foreign DNA molecules and chromosomal fragments are generally eliminated from proliferating cells, but we know little about how mammalian cells prevent their propagation. Here, we show that dividing human and canine cells partition transfected plasmid DNA asymmetrically, preferentially into the daug...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Xuan, Le, Nhung, Denoth-Lippuner, Annina, Barral, Yves, Kroschewski, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932973/
https://ncbi.nlm.nih.gov/pubmed/27298340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606091113
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