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Asymmetric partitioning of transfected DNA during mammalian cell division

Foreign DNA molecules and chromosomal fragments are generally eliminated from proliferating cells, but we know little about how mammalian cells prevent their propagation. Here, we show that dividing human and canine cells partition transfected plasmid DNA asymmetrically, preferentially into the daug...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Wang, Xuan, Le, Nhung, Denoth-Lippuner, Annina, Barral, Yves, Kroschewski, Ruth
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932973/
https://ncbi.nlm.nih.gov/pubmed/27298340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606091113
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