Dynamic JUNQ inclusion bodies are asymmetrically inherited in mammalian cell lines through the asymmetric partitioning of vimentin

Aging is associated with the accumulation of several types of damage: in particular, damage to the proteome. Recent work points to a conserved replicative rejuvenation mechanism that works by preventing the inheritance of damaged and misfolded proteins by specific cells during division. Asymmetric i...

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Главные авторы: Ogrodnik, Mikołaj, Salmonowicz, Hanna, Brown, Rachel, Turkowska, Joanna, Średniawa, Władysław, Pattabiraman, Sundararaghavan, Amen, Triana, Abraham, Ayelet-chen, Eichler, Noam, Lyakhovetsky, Roman, Kaganovich, Daniel
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2014
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050583/
https://ncbi.nlm.nih.gov/pubmed/24843142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1324035111
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